People > Emeritus Faculty

Sinclair Yee


Sinclair Yee
Professor Emeritus
Circuits and Sensors
M226 EE/CSE Bldg.
Box 352500
University of WA
Seattle, WA 98195
Phone: (206) 543-2894
E-mail: yee@ee.washington.edu

Case Western Reserve University 1972 Bioengineering
University of California-Berkeley, Ph.D. 1965 Electrical Engineering
University of California-Berkeley, M.S. 1961 Electrical Engineering
University of California-Berkeley, B.S. 1959 Electrical Engineering


Research Interests

Surface plasmon resonance optical sensors and systems. Metal oxide integrated microsensor arrays.

Optical Sensor Group: http://www.ee.washington.edu/research/spr/

Research Projects

SPR sensor instrumentation for high resolution refractometry and biomolecule interaction analysis; Novel optical configurations of SPR sensors (SPR fiber optic probe, SPR planar probe sensor, SPR retroreflection probe, optical lightpipe SPR sensor); Multichannel sensing devices and SPR biosensing (SPR sensor with parallel channels, SPR sensors with spectral discrimination of sensing channels using an overlayer); Combination of surface plasmon resonance sensor method with other methods (SPR and anodic stripping voltammetry, SPR and critical angle refractometry); Methods for SPR sensor data analysis.

Selected Publications

J. Homola, S. S. Yee: Surface plasmon resonance sensor based on planar light pipe: theoretical optimization analysis, Sensors and Actuators B 37, 1996.

J. Homola, S. S. Yee: Novel Polarization control scheme for spectral surface plasmon resonance sensors, Sensors and Actuators B 51, 1998.

J. Homola, I. Koudela, and S. Yee: Surface plasmon resonance sensors based on diffraction gratings and prism couplers: sensitivity comparison, Sensors and Actuators B 54, 1999.

J. Homola, S. Yee, G. Gauglitz: Surface plasmon resonance sensors: review, Sensors and Actuators B 54, 1999.

T. M. Chinowsky, L. S. Jung, and S. S. Yee, Optimal linear data analysis
for surface plasmon resonance biosensors, Sens. Act. B 54 (1999) 89-97.

Patents

S. Yee, C. Jung, S. Saban, R. Darling, Surface Plasmon Resonacnce Chemical Electrode Jan 12, 1999; Oct. 25, 1996

K. Johnston and S. Yee, Surface Plasmon Resonance Light Pipe Sensing Probe and Related Interface Optics, Sept. 29, 1998; Oct. 25, 1996.

S. Yee, K. Johnston, and S. Shen, Optical Lightpipe Sensor Based on Surface Plasmon Reonance Oct. 13, 1998, Oct. 25, 1996

S. Karlsen, K. Johnston, S. Yee, Surface plasmon reonance light pipe sensor May19, 1999, Oct. 25, 1996

Active Grants

Optical Sensors and Selective Surface Functionalization, S. Yee, PI, C. Furlong, Genetics Science, Co- PI, C. Campbell, Chemistry, Co-PI, Texas Instruments Incorporated (TI), May, 1996-Dec. 1999.

Donation for support of SPR research and development, 1999.

Development of Biosensors for Marine Applications C. Furlong, PI, Medicine and Genetics, S. Yee, Co-PI, and L. Burgess, Co-PI, CPAC; Washington Sea Grant Program, May, 1997-2000.

Development of Surface Plasmon Resonance Biosensors for Marine Applications,: Sensor Platform Development and Optimization S. Yee, PI, Sea Grant, National Competition for Industrial Fellow for graduate student, Mr. Tim Chinowsky. The corporate partner is TI, Nov., 1997-June, 30, 2000

Advanced Surface Plasmon Resonance Sensors, S. Yee, PI; C. Furlong, Co-PI, Medicines and Genetics, 1998-2001; Center for Processing Analytical Chemistry, (CPAC), UW.

Optical Equipment Donation by Army Research Laboratory, 1999.

Development of Biosensors for Marine Applications C. Furlong, PI, Medicine and Genetics, S. Yee, Co-PI, and L. Burgess, Co-PI, CPAC; Washington Sea Grant Program, May, 1997-2000.

Recent Graduate Students

Tim Chinowsky, EE, Surface Plasmon Resonance Optical Sensing System in Capillaries, June. 2000.

Garet Naninger, EE , Multi-channels SPR Sensing System , June, 2001

Mimi Mar, EE, Co-Advisor, Buddy Ratner, Bioengineering, Development of a Surface Plasomon Resonance Biosensor Using a Plasma Deposited Functionalization Film June, 1999.

Linda Jung, Chemistry, S. Yee, Co-Advisor; Charles Campbell, Advisor, Chemistry, Development of chemistry functionalization surfaces for SPR sensors, Sept. 1999.

Hongbu Lu, Bioengineering, S. Yee, Co-Advisor; B. Ratner, Advisor, Biogr. Development of chemistry functionalization surfaces for overlayer SPR sensors, Sept. 2000.

Editorships

Editor for Sensors and Actuators B. may be approx. 100 hours /year, since 1997-present

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