HONGBO LU
Ph.D. Graduate Student

Department of Bioengineering
University of Washington
Bagley 221, Box 351700
Seattle, WA 98195

Tel: (206) 685-7505, (206) 522-8170
Fax: (206) 685-8665
Email: hongbo@u.washington.edu

Research Interests:

Biosensors and biochips; Surface functionalization; Biocompatible materials; Diagnostic medical devices


Education:

2000 Ph.D. Bioengineering (expected), University of Washington, Seattle, USA

1995 M.S. Material Science and Engineering, Tsinghua University, Beijing, China

1993 B.S. Material Science and Engineering, Tsinghua University, Beijing, China

 

Research Experience:

Ph.D., Graduate research assistant, Department of Bioengineering, University of Washington, Seattle, WA September 1995 - present

  • Developed surface functionalization strategies for surface plasmon resonance multichannel biosensors
  • Synthesized and studied biocompatible biomaterials as biomedical implant coatings
  • Developed functionalized surfaces for straightening DNA molecules and optical restriction mapping

Graduate research assistant, Department of Materials Science and Engineering, Tsinghua University, Beijing, China September 1993 - June 1995

  • Studied induced growth of hydroxyapatite thin film by Langmuir-Blodgett films
  • Synthesized collagen-hydroxyapatite composites as orthopedic implant materials

Research assistant, Department of Materials Science and Engineering, Tsinghua University, Beijing, China September 1993 - June 1995

  • Studied silicide thin film material formation on silicon by ion implantation technique for VLSI applications


Journal Papers:

Biosensors and Surface Functionalization

H. B. Lu, C. T. Campbell, D. G. Castner, Attachment of Poly(ethlyene glycol) onto Gold Surfaces, submitted to Langmuir

J. Homola, H. B. Lu, S. S. Yee, Dual-channel surface plasmon resonance sensor with spectral discrimination of sensing channels using a dielectric overlayer, Electronic Letters, vol. 35 No.3 June 1999, p1105-1106

H. Yokota, F. Johnson, H.B. Lu, R.M. Robinson, A.M. Belu, M.D. Garrison, B.D. Ratner, B.J. Trask, D.L. Miller, A new method for straightening DNA molecules for optical restriction mapping, Nucleic Acids research, 25(1997), 1064

Hydroxyapatite Implant Material Characterization and Synthesis

H. B. Lu, C. T. Campbell, B. D. Ratner, Surface analysis of hydroxyapatite and related calcium phosphates by XPS and TOF-SIMS, submitted to Analytical Chemistry

H. B. Lu, C. L. Ma, H. Cui, L. F. Zhou, R. Z. Wang, F. Z. Cui, Controlled crystallization of calcium phosphates under stearic acid monolayers, Journal of Crystal Growth, 155 (1995) 120-125

C.L. Ma, H.B. Lu, R.Z. Wang, L.F. Zhou, F.Z. Cui, F. Qian, Comparison of controlled crystallization of calcium phosphates under three kinds of monolayers, J. Crystal Growth, 173(1997), 141

F.Z. Cui, L.F. Zhu, H. Cui, C.L. Ma, H. B. Lu, H. D. Li, Phase diagram for controlled crystallization of calcium phosphate under acidic organic monolayers, J. Of Cystal Growth, 169 (1996) 557-562

R.Z. Wang, F.Z. Cui, H.B. Lu, H.B. Wen, H.D. Li, Synthesis of nanophase hydroxyapatite / collagen composite, J. Mater. Sci. Lett., 14(1995) 490-492

C.L. Ma, F. Qian; H.B. Lu, Influence of solution concentration on controlled crystallization of calcium phosphate, Proceedings of the SPIE - the International Society for Optical Engineering, vol. 3175, 1998, 371-375

R.Z. Wang, H.B. Lu, C.L. Ma, H.D. Li, F.Z. Cui, Regulating effect of type I collagen on calcium phosphate growth, Proceeding of 94 C-MRS Meeting, 310-313, November 1994, Beijing, China

C.L. Ma, H.B. Lu, F. Qian, C. Zhang, F.Z. Cui, H.D. Li, Study of phase transformation of calcium phosphates under control of organic monolayers, Proceeding of 96 C-MRS Meetings, III-1, 230-234, 1996

Silicide thin film synthesis

B.X. Liu, D.H. Zhu, H.B. Lu, F. Pan, K. Tao, Synthesis of æ- and ß-FeSi2 phases by Fe ion implantation into Si using Metal Vapor Vacuum Arc Ion Source, J. Appl. Phys., 75(1994), 3847

D.H. Zhu, H.B. Lu, K. Tao, B.X. Liu, A preliminary study of the formation of WSi2 by high current W ion implantation, J. Phys.: Condensed Mater, 5(1993), 5505

B.X. Liu, D.H. Zhu, H.B. Lu, A new ion beam technique for synthesis metal-silicides, Physics 23 (2), 1994 (Chinese)

D.H. Zhu, H.B. Lu, B.X. Liu, Study of Ti-sillicide formation using high current metal ion source, Chinese Journal of Semiconductors, vol.16, No.3, 1995, 229-234 (Chinese)

D.H. Zhu, H.B. Lu, F. Pan, B.X. Liu, C54-TiSi2 fabricated by direct ion beam synthesis, Transaction of Material Research Society, Japan, vol 14B, ICAM'93 B: Magnetic, Fullerene, Dielectric, Ferroelectric, Diamond and Related Materials, edited by M. Homma et al, September 1993


Conference Abstracts and Presentations:

Biosensors and Surface Functionalization

H. B. Lu, J. Homola, B. D. Ratner, C. T. Campbell, S. S. Yee, Surface Functionalization Strategies for Miniature Multichannel Biosensing, International meeting of American Vacuum Society, October 1999, Seattle WA

J. Homola, H. B. Lu, S.S. Yee, C.T. Campbell, Novel approach to mulstichannel SPR sensing, Photonics East, 19-22 September 1999, Boston, Massachusetts

H. B. Lu, C. T. Campbell, D. G. Castner, B. D. Ratner, Functionalized Poly(Ethylene Glycol) Films on Gold for Surface Plasmon Resonance Biosensing, Symposium on Non-fouling Surface Technologies, July 30-31, 1998, Seattle, WA

H.B. Lu, L. S. Jung, C.T. Campbell, K. Nelson, P. Stayton, M. Mar, S. Yee, Study of protein adsorption at interface by surface plasmon resonance sensor, 1st International Protein at Interface Conference, August, 1997, Seattle, WA

L. S. Jung, H.B. Lu, C. T. Campbell, Sensors based on functionalized surface plasma resonance device, 213th ACS national meeting, April 13-17, 1997

Hydroxyapatite Implant Biomaterial characterization and Synthesis

H. B. Lu, C. T. Campbell, B. D. Ratner Characterization of Apatite and Related Calcium Phosphates Surfaces by XPS and TOF-SIMS, 217th National Meeting and Exposition of the American Chemical Society, March 21-25, 1999, Anaheim, CA

H. B. L, C. T. Campbell, B. D. Ratner, Surface analysis of apatite and related calcium phosphates by XPS, Surface analysis of apatite and related calcium phosphates by XPS, Society For Biomaterials, 24th Annual Meeting in conjunction with the 30th International Biomaterials Symposium, April 22-26, 1998, San Diego, CA

R.Z. Wang, H.B. Lu, C.L. Ma, H.D. Li, and F.Z. Cu Regulating growth of calcium phosphates by type I collagen, 3rd Int. Symp. on Applied Bioinorganic Chem., December 1994, Fremantle

Silicide thin film synthesis

B.X. Liu, D.H. Zhu, H.B. Lu, K. Tao, MEVVA ion source to synthesize refractory metal silicides, MRS Fall Meeting, November, 1993, Boston.

D.H. Zhu, H.B. Lu, F. Pan, B.X. Liu, C54-TiSi2 fabricated by direct ion beam synthesis, ICAM'93, Sepetmeber, 1993, Tokyo