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Research Interests:
Guided-wave optics, photonic devices, optical sensors.
Education:
1993 Ph.D. Electrical Engineering, Academy of Sciences of the Czech Republic,
Prague
1988 M.S. Physical Engineering, Czech Technical University, Prague, Czech
Republic
Professional Activities:
Member of Permanent Steering Committee, Advanced Study Course on Optical
Chemical Sensors
Member of Permanent Steering Committee, Europt(r)ode
Conference Series
Member of International Program Committee, 7th Vienna Opt(r)ode Workshop,
October 1996 Regensburg, Germany
Member of International Scientific Committee, 4th European Conference
on Optical Chemical Sensors and Biosensors, March 29 - April 1, 1998,
Munster, Germany
Member of International Program Committee, 8th Vienna Opt(r)ode Workshop,
October 7- 8, 1998, Prague, Czech Republic
Guest Associate Editor for Special Issue: Surface Plasmon Resonance (SPR)
Optical Sensors, Current Technology and Applications, Sensors and Actuators
B, 1999
Reviewed research manuscripts
for Sensors and Actuators B, Applied Physics Letters, Measurement Science
and Technology, Analytical Chemistry
Reviewed research project
proposals for US National Science Foundation, US Department of Agriculture,
US National Institutes of Health
Member of European Optical
Society, Czechoslovak Society for Photonics, Czech Electrotechnical Society
Publications :
Books
J. Homola, S. S. Yee, D. Myszka: Surface plasmon biosensors, in Optical
Biosensors: Present and Future (editor F. S. Ligler), to be published
in 2002.
Journal
Papers
J. Homola: Model of a chemooptical sensor based on surface plasmon excitation
in thin silver films, Sensors and Actuators B 11, 481 - 485 (1993).
J. Ctyroký, J. Homola: Modeling of surface plasmon resonance waveguide
sensor by complex mode expansion and propagation method, Optical and Quantum
Electronics 29, 301 - 311 (1997).
J. Homola: Optical fiber sensor based on surface plasmon excitation, Sensors
and Actuators B 29, 401 - 405 (1995).
J. Homola, R. Slavík: Fiber-optic sensor based on surface plasmon resonance,
Electronics Letters 32, 480 - 482 (1996).
J. Homola, J. Ctyroký, M. Skalský, J. Hradilová, P. Kolárová: A surface
plasmon resonance based integrated optical sensor, Sensors and Actuators
B 38 - 39, 286 - 290 (1997).
J. Homola, S. S. Yee: Surface plasmon resonance sensor based on planar
light pipe: theoretical optimization analysis, Sensors and Actuators B
37, 145 - 150 (1996).
J. Homola: On the sensitivity of surface plasmon resonance sensors with
spectral interrogation, Sensors and Actuators B 41,207 - 211 (1997).
J. Homola, R. Slavík, J. Ctyroký: Interaction between fiber modes and
surface plasmon waves: spectral properties, Optics Letters 22, 1403 -
1405 (1997).
J. Ctyroký, J. Homola, M. Skalský: Tuning of spectral operation range
of a waveguide surface plasmon resonance sensor, Electronics Letters 33,
1246 - 1248 (1997).
J. Homola, S. S. Yee: Novel Polarization control scheme for spectral surface
plasmon resonance sensors, Sensors and Actuators B 51, 331-339 (1998).
R. Slavík, J. Homola, J. Ctyroký: Miniaturization of fiber optic surface
plasmon resonance sensor, Sensors and Actuators B 51, 311-315 (1998).
J. E. Dyr, I. Tichý, M. Jiroušková, P. Tobiška, R. Slavík, J. Homola,
E. Brynda, M. Houska, J. Suttnar: Molecular arrangement of adsorbed fibrinogen
molecules characterized by specific monoclonal antibodies and a surface
plasmon resonance sensor, Sensors and Actuators B 51, 268-272 (1998).
J. E. Dyr, I. Tichý, M. Jiroušková, P. Tobiška, R. Slavík, J. Homola,
and J. Suttnar: Real-time sensing of surface-bound fibrinogen and fibrin
interactions using spectroscopy of guided modes in optical waveguide structures,
surface plasmon resonance, and specific monoclonal antibodies, Blood Coagulation
and Fibrinolysis 9, 675 (1998).
R. Slavík, J. Homola, J. Ctyroký: Single-mode optical fiber surface plasmon
resonance sensor, Sensors and Actuators B 54, 74-79 (1999).
E. Brynda, J. Homola, M. Houska, P. Pfeifer, J. Škvor, Antibody networks
for surface plasmon resonance immunosensors, Sensors and Actuators B 54,
132-136 (1999).
J. Ctyroký, J. Homola, P. V. Lambeck, S. Musa, H. J. W. M. Hoekstra, R.
D. Harris, J. S. Wilkinson, B. Usievich, N. M. Lyndin, Theory and modeling
of optical waveguide sensors utilizing surface plasmon resonance, Sensors
and Actuators B 54, 66-73 (1999).
J. Homola, I. Koudela, and S. Yee: Surface plasmon resonance sensors based
on diffraction gratings and prism couplers: sensitivity comparison, Sensors
and Actuators B 54, 16-24 (1999).
J. Homola, S. Yee, G. Gauglitz: Surface plasmon resonance sensors: review,
Sensors and Actuators B 54, 3-15 (1999).
J. Homola, H. B. Lu, and S.
S. Yee, Dual-channel surface plasmon resonance sensor with spectral discrimination
of sensing channels using a dielectric overlayer, Electronics Letters
35, 1105-1106 (1999).
J. Ryšavá, J.E.Dyr, J.Suttnar,
P.Cieslar, E.Brynda, M. Houska, A. Brandenburg, J. Homola: Thrombogenicity
of fibrinogen layers, Chemické listy 8, 565 (2000).
J. E. Dyr, J. Ryšavá, J.
Suttnar, J. Homola, P. Tobiška, Optical sensing of the initial stages
in the growth and development of fibrin clot, Sensors and Actuators 74,
69-73 (2001).
R. Slavík, J. Homola, J.
Ctyroký: Novel spectral fiber optic sensor based on surface plasmon resonance,
Sensors and Actuators 74, 106-111 (2001).
G. G. Nenninger, P. Tobiška,
J. Homola, S. S. Yee: Long-range surface plasmons for high-resolution
surface plasmon resonance sensors, Sensors and Actuators 74, 145-151 (2001).
V. Koubová, E. Brynda, L.
Karasová, J. Škvor, J. Homola, J. Dostálek, P. Tobiška, J. Rošický: Detection
of foodborne pathogens using surface plasmon resonance biosensors, Sensors
and Actuators 74, 100-105 (2001).
H. B. Lu, J. Homola, S.
S. Yee, C. T. Campbell, B. D. Ratner: Surface functionalization of dual-channel
surface plasmon resonance biosensor by protein contact printing, Sensors
and Actuators 74, 91-99 (2001).
J. Homola, H. B. Lu, G.
G. Nenninger J. Dostálek, S. S. Yee: A novel multichannel surface plasmon
resonance biosensor, Sensors and Actuators, 76, 403-410 (2001).
J. Dostálek, J. Ctyroký,
J. Homola, E. Brynda, M. Skalský, P. Nekvindová, J. Špirková, J. Škvor,
J. Schröfel: Surface plasmon resonance biosensor based on integrated optical
waveguide, Sensors and Actuators, 76, 8-12 (2001).
Invited Conference Papers
J. Homola, J. Ctyroký: Surface plasmon resonance sensors, 7th Vienna Opt(r)rode
Workshop, Regensburg, Germany, October 1996, Proceedings of Workshop.
J. Homola, S. Yee: Recent developments in surface plasmon resonance sensing,
8th Vienna Opt(r)ode Workshop, Prague, Czech Republic, October 1998.
J. Homola: Surface plasmon resonance biosensors,
5th European Conference on Optical Sensors and Biosensors, Lyon, France,
April 16-19, 2000.
J. Homola: Optical biosensors
based on spectroscopy of guided waves, Advanced Study Course on Optical
Chemical Sensors, Rogaška-Slatina, Slovenia, September 24-28, 2000.
J. Homola: Affinity biosensors
based on surface plasmon resonance, 8th European Conference on Organised
Films (ECOF8), Otranto, Italy, September 3- 7, 2001
J. Homola: Advances in surface
plasmon resonance biosensing, Optical Sensors 2001, Prague, Czech Republic,
October 1-3, 2001.
Conference Papers
J. Homola: Model of a chemooptical sensor based on surface plasmon excitation
in thin silver films, 1st European Conference on Optical Chemical Sensors
and Biosensors, Graz, Austria, April 1992.
J. Homola: Measurement of optical constants of thin metal films by means
of ATR method, Photonics 92, Olomouc, Czech Republic, September 1992,
Proceedings of the conference Photonics 92, 208 - 214.
J. Homola: Surface plasmon optical fiber polarizer, Optical Communications
OK'94, Prague, Czech Republic, March 1994, Proceedings OK'94, 112 - 113.
J. Homola: Chemical fiber optic sensor employing surface plasmon excitation,
2nd European Conference on Optical Chemical Sensors and Biosensors, Firenze,
Italy, April 1994.
J. Homola: Thin films study by means of optically excited surface plasmons,
Nano'94 - International Conference on Nanometrology Scanning Probe Microscopy
and Related Techniques, Brno, Czech Rep., August 1994, Proceedings Nano'94,
84 - 87.
J. Homola, G. Schwotzer, H. Lehmann, R. Willsch, W. Ecke, H. Bartelt:
Fiber optic sensor for adsorption studies using surface plasmon resonance,
European Symposium on Optics for Environmental and Public Safety, Munich,
Germany, June 1995, Proc. SPIE Vol. 2508, 324 - 333 (1995).
J. Homola, J. Ctyroký, M. Skalský, J. Hradilová, P. Kolárová: Integrated-optic
waveguide sensor based on surface plasmon resonance: analysis and design,
Photonics'95, Prague, Czech Republic, August 1995, EOS Annual Meeting
Digest Series, Vol. 2A, 210 - 213.
J. Homola, G. Schwotzer, H. Lehmann, R. Willsch, W. Ecke, H. Bartelt:
A new optical fiber sensor for humidity measurement, Photonics'95, Prague,
Czech Republic, August 1995, EOS Annual Meeting Digest Series, Vol. 2A,
245 - 248.
J. Ctyroký, J. Homola: Modeling of surface plasmon resonance waveguide
sensor by complex mode expansion and propagation method, International
Workshop on Optical Waveguide Theory and Numerical Modeling, Roosendaal,
Netherlands, September 1995.
J. Homola, J. Ctyroký, M. Skalský, J. Hradilová, P. Kolárová: A surface
plasmon resonance based integrated optical sensor, 3rd European Conference
on Optical Chemical Sensors and Biosensors, Zurich, Switzerland, April
1996.
J. Homola, R. Slavík, J. Ctyroký: Surface plasmon resonance sensors using
optical waveguides, Third Conference on Photonic Systems for Ecological
Monitoring, Prague, Czech Republic, December 1996, Proc. SPIE Vol. 3200,
100-106 (1997).
J. Ctyroký, J. Homola, M. Skalský: Spectral properties of a surface plasmon
resonance sensor structure, ECIO'97 - 8th European Conference on Integrated
Optics, Stockholm, Sweden, April 1997, Proceedings ECIO'97, 452 - 455.
J. Homola, P. Pfeifer, E. Brynda, J. Škvor, M. Houska, G. Schwotzer, I.
Latka, R. Willsch: Optical biosensing using surface plasmon resonance
spectroscopy, Chemical, Biochemical and Environmental Fiber Sensors IX,
Munich, Germany, June 1997, Proc. SPIE Vol. 3105, 318 - 324 (1997).
R. Slavík, J. Homola, J. Ctyroký: Novel surface plasmon resonance sensor
based on single-mode optical fiber, Chemical, Biochemical and Environmental
Fiber Sensors IX, Munich, Germany, June 1997, Proc. SPIE Vol. 3105, 325
- 331 (1997).
R. Slavík, J. Homola, J. Ctyroký: Optical fiber surface plasmon resonance
sensor for an aqueous environment, 12th International Conference on Optical
Fiber Sensors, Williamsburg, USA, October 1997, Technical Digest Series
16, 436 - 439 (1997).
J. Homola, S. S. Yee: Novel polarization control scheme for spectral surface
plasmon resonance sensors, EUROPT(R)ODE IV, Münster, Germany, March 29
- April1, 1998.
R. Slavík, J. Homola, J. Ctyroký: Miniaturization of fiber optic surface
plasmon resonance sensor, EUROPT(R)ODE IV, Münster, Germany, March 29
- April1, 1998.
J. E Dyr, I. Tichý, P. Tobiška, R. Slavík, J. Homola, E. Brynda, M. Houska,
and J. Suttnar, Study of molecular arrangement of adsorbed fibrinogen
molecules using specific monoclonal antibodies and a surface plasmon resonance
sensor, EUROPT(R)ODE IV, Münster, Germany, March 29 - April1, 1998.
R. Slavík, E. Brynda, J. Homola, and J. Ctyroký: Miniature fiber optic
surface plasmon resonance immunosensor, BiOS Europe 98, Medical Sensors
V and Fiber Optic Sensors IV, September 1998, Stockholm, Sweden, Proceedings
SPIE, Vol. 3570, 184-191.
J. E. Dyr, M. Jiroušková, J. Ryšavá, I. Tichý, P. Tobiška, R. Slavík,
J. Homola, and J. Suttnar: Surface plasmon resonance analysis of immobilized
fibrin and its interaction with thrombin and fibrinogen, BiOS Europe 98,
Medical Sensors V and Fiber Optic Sensors IV, September 1998, Stockholm,
Sweden, Proceedings SPIE, Vol. 3570, 176-183.
E. Brynda, M. Houska, P. Tobiška, J. Homola: The suppression of non-specific
response to human blood plasma in SPR sensor for detection of b2microglobulin,
8th Vienna Opt(r)ode Workshop, Prague, Czech Republic, October 1998.
R. Slavík, E. Brynda, J. Homola, and J. Ctyroký: Miniature fiber optic
surface plasmon resonance immunosensor, 8th Vienna Opt(r)ode Workshop,
Prague, Czech Republic, October 1998.
J. Homola, E. Brynda, P. Tobiška, I. Tichý: Optical biosensors using surface
plasmon resonance, PHOTONICS PRAGUE'99, 21- 23 June 1999, Prague, Czech
Republic, to be published in Proc. SPIE.
R. Slavík. J. Ctyroký, J. Homola: Fibre Optic Surface Plasmon Resonance
Sensor with a Fiber Bragg Grating, PHOTONICS PRAGUE'99, 21- 23 June 1999,
Prague, Czech Republic, to be published in Proc. SPIE.
J. Homola, H. B. Lu, S. S. Yee and C. T. Campbell, Novel approach to multichannel
SPR sensing, Photonics East, 19-22 September 1999, Boston, USA, accepted
for presentation.
E. Brynda, M. Houska, J. Homola, A. Wikerstal:
Detection of analytes of various dimensions, ASCOS99, Neusidel, Austria,
September 27-29,1999, Book of Abstracts, Keynote 2.
E. Brynda, M. Houska, J. Homola, A. Wikerstal,
A. Brandenburg: Binding of ligands to immobilized bioreceptors-dimensional
aspects, 3rd International Workshop on Molecular Recognition at Surfaces,
Basel, Switzerland, November 25-27, 1999, MEMOCS newsletters.
H. B. Lu, J. Homola, C. T. Campbell, B. D. Ratner,
S. S. Yee: Surface functionalization strategies for miniature multichannel
biosensing, International Symposium of American Vacuum Society, October
25-29, 1999, Seattle, USA, Book of Abstracts, 107.
J. Homola, S. S. Yee: Affinity biosensing using
surface plasmon resonance, Fourteenth International Forum Process Analytical
Chemistry- IFPAC 2000, Las Vegas, USA, January 23-26, 2000, Book of Abstracts,
Abstract I-069.
J. Homola, G. G. Nenninger, H. B. Lu, A. N. Naimushin,
S. B. Soelberg, S. S. Yee, C. E. Furlong: Surface plasmon resonance biosensors
for detection and identification of biological warfare agents, 2000 MASINT
Biological Warfare Science and Technology Symposium, Long Beach, USA,
January 10-13, 2000.
H. B. Lu, J. Homola, S. S. Yee, C. T. Campbell,
B. D. Ratner: Surface functionalization strategies for a novel self-referencing
surface plasmon resonance dual-channel biosensor, Chemical Sensors & Interfacial
Design, Gordon Research Conference, Ventura, USA, January 23-28, 2000.
J. Homola, S. S. Yee: Surface plasmon resonance
biosensors, Sensor Technologies: Needs and Assessment Symposium, Development
and Integration of Advances in Measurement Technology for Applications
in Biotechnology, Pharmaceuticals, and Food Safety, Santa Fe, USA, February
28-29, 2000.
H. B. Lu, J. Homola, G. G. Nenninger, A. N. Naimushin,
S. B. Soelberg, S. S. Yee, C. E. Furlong: Surface plasmon resonance biosensor
development: surface functionalization, Needs and Assessment Symposium,
Development and Integration of Advances in Measurement Technology for
Applications in Biotechnology, Pharmaceuticals, and Food Safety, Santa
Fe, USA, February 28-29, 2000.
M. Piliarik, J. Homola, J. Dostálek, P. Tobiška,
J. Rošický: Non-linear regression data analysis method for high resolution
surface plasmon resonance sensors, 5th European Conference on Optical
Sensors and Biosensors, Lyon, France, April 16-19, 2000, Book of Abstracts,
167 - 168.
E. Brynda, J. Homola, V. Koubová, J. Dostálek,
J. Rošický, J. Škvor, P. Rauch: Detection of foodborne pathogens using
surface plasmon resonance biosensors, 5th European Conference on Optical
Sensors and Biosensors, Lyon, France, April 16-19, 2000, Book of Abstracts,
163 - 164.
H. B. Lu, J. Homola, S. S. Yee, C. T. Campbell,
B. D. Ratner: Surface functionalization of dual-channel surface plasmon
resonance biosensor by protein contact printing, 5th European Conference
on Optical Sensors and Biosensors, Lyon, France, April 16-19, 2000, Book
of Abstracts, 161 - 162.
R. Slavík, J. Homola, J. Ctyroký: Novel spectral
fiber optic sensor based on surface plasmon resonance, 5th European Conference
on Optical Sensors and Biosensors, Lyon, France, April 16-19, 2000, Book
of Abstracts, 165 - 166.
G. G. Nenninger, P. Tobiška, J. Homola, S. S. Yee:
Long-range surface plasmons for high-resolution surface plasmon resonance
sensors, 5th European Conference on Optical Sensors and Biosensors, Lyon,
France, April 16-19, 2000, Book of Abstracts, 203 - 204.
J. E. Dyr, J. Ryšavá, J. Suttnar, J. Homola, P.
Tobiška, I. Tichý, J. Dostálek, E. Brynda, M. Houska: Optical sensor-based
observation of initial stages in the growth and development of fibrin
clot, 5th European Conference on Optical Sensors and Biosensors, Lyon,
France, April 16-19, 2000, Book of Abstracts 147 - 148.
H. B. Lu, J. Homola, V.
Y. Pan, C. T. Campbell, B. D. Ratner, S. S. Yee: Surface functionalization
for self-referencing surface plasmon resonance biosensors by rf-plasma-deposited
thin films and self-assembled monolayers, Sixth World Biomaterials Congress,
Kamuela, Hawaii, U.S.A., May 15-20, 2000.
J. Homola, H. B. Lu, J.
Dostálek, S. S. Yee, C. T. Campbell, B. D. Ratner: A novel multichannel
surface plasmon resonance biosensor, 8th International Meeting on Chemical
Sensors, Basel, Switzerland, July 3-5, 2000, Book of Abstracts, 46.
H. B. Lu, J. Homola, S.
S. Yee, C. T. Campbell, B. D. Ratner: Surface functionalization of surface
plasmon resonance biosensors with on-chip reference feature, 8th International
Meeting on Chemical Sensors, Basel, Switzerland, July 3-5, 2000, Book
of Abstracts, 144.
J. Ctyroký, J. Homola, E.
Brynda, M. Skalský, J. Dostálek, J. Schrofel: Surface plasmon resonance
biosensors based on integrated optical waveguides, 8th International Meeting
on Chemical Sensors, Basel, Switzerland, July 3-5, 2000, Book of Abstracts,
34.
J. Homola, M. Piliarik,
R. Slavík, J. Ctyroký: Advances in development of miniature fiber optic
surface plasmon resonance sensors, Optical Engineering for Sensing and
Nanotechnology, Yokohama, Japan, June 6-8, 2001, SPIE Proceedings, Vol.
4416, 82-85.
J. Homola, J. Dostálek,
J. Ctyroký: Novel approach to surface plasmon resonance multichannel sensing,
Optical Engineering for Sensing and Nanotechnology, Yokohama, Japan, June
6-8, 2001, SPIE Proceedings, Vol. 4416, 86-89.
J. Homola, J. Dostálek,
S. Chen, A. Rasooly, S. Jiang, S. S. Yee: Reference-compensated surface
plasmon resonance biosensor for detection of foodborne pathogens, Optical
Engineering for Sensing and Nanotechnology, Yokohama, Japan, June 6-8,
2001, SPIE Proceedings, Vol. 4416, 280-283.
P. Tobiška, G. G. Nenninger,
J. Homola, S. S. Yee, Improving resolution of surface plasmon resonance
sensors by employing long-range surface plasmons, Optical Sensors 2001,
Prague, Czech Republic, October 1-3, 2001.
M. Piliarik, J. Homola,
J. Ctyroký, R. Slavík, Novel approach to miniaturization of surface plasmon
resonance biosensors, Optical Sensors 2001, Prague, Czech Republic, October
1-3, 2001.
J. Ryšavá, J. Homola, J.
E. Dyr, J. Suttnar, P. Tobiška, I. Tichý, J. Dostálek, P. Krízová: Fibrin
clot formation observed by optical biosensors, Optical Sensors 2001, Prague,
Czech Republic, October 1-3, 2001.
J. Ryšavá, J. Homola, E.
Brynda, M. Houska, J. Suttnar, P. Tobiška, I. Tichý, J. Dostálek, J. E.
Dyr, P. Krízová: Real time observation of fibrinogen adhesion using surface
plasmon resonance and grating coupler, Optical Sensors 2001, Prague, Czech
Republic, October 1-3, 2001.
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