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Azadeh Yazdan-Shahmorad

  • Assistant Professor

Appointments

Assistant Professor, Bioengineering
Assistant Professor, Electrical Engineering
Core staff scientist, Washington National Primate Center, Division of Neuroscience

Biography

Azadeh Yazdan-Shahmorad joined the University of Washington this fall as the Washington Research Foundation Innovation Assistant Professor of Neuroengineering in the departments of bioengineering and electrical engineering. Yazdan-Shahmorad is the recipient of two postdoctoral fellowships from the American Heart Association, providing funding for her research at the University of California, San Francisco. She has developed new tools and techniques for implementing optogenetics in non-human primates (NHPs) and rats, and she currently uses these tools to induce and study targeted plasticity in sensorimotor connections in NHPs. Her long-term goal is to use neural technologies to develop stimulation-based therapies to help restore function and mobility in people with neurological disorders such as stroke. She received bachelor’s and master’s degrees in biomedical engineering at Tehran Polytechnic University and University of Tehran, Iran, respectively, and earned her Ph.D. in biomedical engineering from the University of Michigan in 2011. Yazdan-Shahmorad is the recipient of the 2014 IEEE Brain Grand Challenges Young Investigator Award. Her research in targeted sensorimotor plasticity was selected as a hot topic of 2016 by the Society for Neuroscience.

Research Interests

Neural Engineering,  Neural interfaces, Optogenetics, Brain stimulation, Neurorehabilitation, Stroke rehabilitation, Stimulation-based therapies.

Representative Publications

  • A. Yazdan-Shahmorad, M. J. Lehmkuhle, G. J. Gage, H. Parikh, T. Marzullo, R. M. Miriani and D. R. Kipke, “Estimation of electrode location in rat motor cortex by laminar analysis of electrophysiology and intracortical electrical stimulation” Journal of Neural Engineering. 8 (2011) 046018. PMID: 21690656. [ Link ]
  • A. Yazdan-Shahmorad, D. R. Kipke, M. J. Lehmkuhle, “Polarity of cortical electrical stimulation differentially affects neuronal activity of deep and superficial layers of rat motor cortex”, Brain Stimulation Journal (2011). Oct;4(4):228-41. PMID: 22032738, PMCID: PMC3204189. [ Link ]
  • A. Yazdan-Shahmorad, D. R. Kipke, M. J. Lehmkuhle, “High gamma power in ECoG reflects cortical electrical stimulation effects on unit activity in layers V/VI”, Journal of Neural Engineering. 10 (2013) 066002. PMID: 24099908, PMCID: PMC4140191. [ Link ]
  • P. Ledochowitsch*, A. Yazdan-Shahmorad* (Equal contribution), K. E. Bouchard, C. Diaz-Botia, T. L. Hanson, J.W. He, B. Seyboldt, E. Olivero, E. A. K. Phillips, T. J. Blanche, C. E. Schreiner, A. Hasenstaub, E. F. Chang, P. N. Sabes, M. M. Maharbiz, “Strategies for optical control and simultaneous electrical readout of extended cortical circuits”, Journal of Neuroscience methods (2015). Dec;256:220-31. PMID: 26296286. [ Link ]
  • A. Yazdan-Shahmorad, C. Diaz-Botia, T. Hanson, P. Ledochowitsch, M. M. Maharbiz, P. Sabes, “A large interface for optogentic stimulation and recording in non-human primates”, Neuron; 2016 Feb 10. PMID: 26875625. [ Link ]

Research Labs

Research Areas

Education

  • Ph.D in Biomedical Engineering, 2011
    University of Michigan
  • M.S. Electrical Engineering (Bioelectric Engineering), 2003
    University of Tehran
  • B.S. in Biomedical Engineering, 2001
    Tehran Polytechnic